Medical treatment as an alternative to adrenalectomy in patients with aldosterone-producing adenomas.
| Τίτλος | Medical treatment as an alternative to adrenalectomy in patients with aldosterone-producing adenomas. |
| Publication Type | Journal Article |
| Year of Publication | 2008 |
| Authors | Karagiannis, A., Tziomalos K., Kakafika A. I., Athyros V. G., Harsoulis F., & Mikhailidis D. P. |
| Journal | Endocr Relat Cancer |
| Volume | 15 |
| Issue | 3 |
| Pagination | 693-700 |
| Date Published | 2008 Sep |
| ISSN | 1351-0088 |
| Λέξεις κλειδιά | Adrenal Cortex Neoplasms, Adrenalectomy, Adrenocortical Adenoma, Aldosterone, Humans, Hyperaldosteronism, Mineralocorticoid Receptor Antagonists |
| Abstract | Primary aldosteronism (PA) and, in particular, its two commonest subtypes (i.e. idiopathic hyperaldosteronism (IHA) and aldosterone-producing adenoma (APA)) have been recognized as the most common cause of secondary hypertension. While 'conservative' medical treatment with aldosterone receptor antagonists is the therapeutic approach of choice in controlling blood pressure in patients with PA due to IHA, the more invasive (laparoscopic) adrenalectomy seems to be the most suitable therapy for patients with APA. In this review, we focus on the medical approach for the management of APA in cases where surgical excision of the adrenal is not possible. |
| DOI | 10.1677/ERC-08-0094 |
| Alternate Journal | Endocr. Relat. Cancer |
| PubMed ID | 18586836 |
