Circulating activin-A is elevated in postmenopausal women with low bone mass: the three-month effect of zoledronic acid treatment.
Τίτλος | Circulating activin-A is elevated in postmenopausal women with low bone mass: the three-month effect of zoledronic acid treatment. |
Publication Type | Journal Article |
Year of Publication | 2013 |
Authors | Anastasilakis, A. D., Polyzos S. A., Makras P., Gkiomisi A., Savvides M., Papatheodorou A., & Terpos E. |
Journal | Osteoporos Int |
Volume | 24 |
Issue | 7 |
Pagination | 2127-32 |
Date Published | 2013 Jul |
ISSN | 1433-2965 |
Λέξεις κλειδιά | Activins, Age Factors, Aged, Aging, Biomarkers, Bone Density, Bone Density Conservation Agents, Case-Control Studies, Diphosphonates, Female, Femur Neck, Humans, Imidazoles, Lumbar Vertebrae, Middle Aged, Osteoporosis, Postmenopausal, Prospective Studies, Zoledronic Acid |
Abstract | UNLABELLED: Activin-A is expressed in bone and seems to regulate osteoclastogenesis. In this study, serum activin-A was increased in postmenopausal women with low bone mass and was positively correlated to age and negatively to lumbar spinal bone mineral density (BMD). Serum activin-A levels did not change 3 months after zoledronic acid infusion. |
DOI | 10.1007/s00198-012-2198-0 |
Alternate Journal | Osteoporos Int |
PubMed ID | 23124716 |