Association of exfoliation syndrome and central retinal vein occlusion: an ultrastructural analysis.
Τίτλος | Association of exfoliation syndrome and central retinal vein occlusion: an ultrastructural analysis. |
Publication Type | Journal Article |
Year of Publication | 2010 |
Authors | Ritch, R., Prata T. S., de Moraes C. Gustavo V., Vessani R. M., Costa V. P., Konstas A. G. P., Liebmann J. M., & Schlötzer-Schrehardt U. |
Journal | Acta Ophthalmol |
Volume | 88 |
Issue | 1 |
Pagination | 91-5 |
Date Published | 2010 Feb |
ISSN | 1755-3768 |
Λέξεις κλειδιά | Aged, Aged, 80 and over, Conjunctiva, Exfoliation Syndrome, Female, Humans, Incidence, Male, Microscopy, Electron, Middle Aged, Prospective Studies, Retinal Vein Occlusion |
Abstract | PURPOSE: To evaluate prospectively the frequency with which exfoliation syndrome (XFS) occurs in patients with central retinal vein occlusion (CRVO) by clinical examination and ultrastructural examination of conjunctival biopsy specimens.METHODS: Prospective observational case series. Thirty-six eyes of 36 consecutive patients with CRVO were investigated for XFS by slit-lamp examination and conjunctival biopsy when XFS was not clinically visible on examination.RESULTS: A clinical diagnosis of XFS or a positive biopsy result for exfoliation material (XFM) was present in 22 of the 36 patients (61%; 95% confidence interval 45-75%). Twelve of these 22 patients (54%) had a clinical diagnosis of XFS. Aggregates of XFM were identified ultrastructurally in the biopsy specimens in 10 of 24 patients with no clinical signs of XFS (42%). Patients with and without XFS had similar distribution of age, gender, race and prevalence of systemic disorders. Twelve of the 22 (54%) XFS patients had neither glaucoma nor ocular hypertension prior to the CRVO.CONCLUSION: In accordance with previous retrospective and histological studies, this prospective, in vivo study suggests that CRVO is commonly associated with XFS. |
DOI | 10.1111/j.1755-3768.2009.01578.x |
Alternate Journal | Acta Ophthalmol |
PubMed ID | 19725816 |