Olmesartan ameliorates urinary dysfunction in the spontaneously hypertensive rat via recovering bladder blood flow and decreasing oxidative stress.
Τίτλος | Olmesartan ameliorates urinary dysfunction in the spontaneously hypertensive rat via recovering bladder blood flow and decreasing oxidative stress. |
Publication Type | Journal Article |
Year of Publication | 2014 |
Authors | Shimizu, S., Saito M., Oiwa H., Ohmasa F., Tsounapi P., Oikawa R., Dimitriadis F., Martin D. T., Satoh I., Kinoshita Y., & Tomita S. |
Journal | Neurourol Urodyn |
Volume | 33 |
Issue | 3 |
Pagination | 350-7 |
Date Published | 2014 Mar |
ISSN | 1520-6777 |
Λέξεις κλειδιά | Aldehydes, Angiotensin II Type 1 Receptor Blockers, Animals, Antihypertensive Agents, Biomarkers, Blood Pressure, Disease Models, Animal, Hypertension, Imidazoles, Male, Malondialdehyde, Nerve Growth Factor, NF-E2-Related Factor 2, Nifedipine, Oxidative Stress, Rats, Rats, Inbred SHR, Rats, Wistar, Regional Blood Flow, Tetrazoles, Urinary Bladder, Urinary Bladder Diseases, Urodynamics |
Abstract | PURPOSE: As hypertension (HT) is one of the risk factors for lower urinary tract symptoms, we investigated the effect of an angiotensin II type I receptor blocker, olmesartan, on bladder dysfunction in the spontaneously hypertensive rat (SHR). |
DOI | 10.1002/nau.22405 |
Alternate Journal | Neurourol Urodyn |
PubMed ID | 23775684 |