Nicorandil ameliorates hypertension-related bladder dysfunction in the rat.
Τίτλος | Nicorandil ameliorates hypertension-related bladder dysfunction in the rat. |
Publication Type | Journal Article |
Year of Publication | 2012 |
Authors | Saito, M., Ohmasa F., Tsounapi P., Inoue S., Dimitriadis F., Kinoshita Y., & Satoh K. |
Journal | Neurourol Urodyn |
Volume | 31 |
Issue | 5 |
Pagination | 695-701 |
Date Published | 2012 Jun |
ISSN | 1520-6777 |
Λέξεις κλειδιά | Animals, Antihypertensive Agents, Blood Pressure, Disease Models, Animal, Enzyme-Linked Immunosorbent Assay, Hypertension, KATP Channels, Male, Nerve Growth Factor, Nicorandil, Potassium Channels, Inwardly Rectifying, Rats, Rats, Inbred SHR, Rats, Wistar, Real-Time Polymerase Chain Reaction, Regional Blood Flow, Reverse Transcriptase Polymerase Chain Reaction, RNA, Messenger, Time Factors, Urinary Bladder, Urinary Bladder, Overactive, Urination, Urodynamics |
Abstract | AIMS: There is increasing evidence that ischemia is one of the main etiology in overactive bladder (OAB), and that nicorandil prevents OAB. We investigated the effect of nicorandil on hypertension-related bladder dysfunction in spontaneously hypertensive rats (SHRs). |
DOI | 10.1002/nau.21213 |
Alternate Journal | Neurourol Urodyn |
PubMed ID | 22473863 |