Adipocytokines in relation to Hodgkin lymphoma in children.
| Τίτλος | Adipocytokines in relation to Hodgkin lymphoma in children. |
| Publication Type | Journal Article |
| Year of Publication | 2010 |
| Authors | Petridou, E. Th, Dessypris N., Panagopoulou P., Sergentanis T. N., Mentis A-F. A., Pourtsidis A., Polychronopoulou S., Kalmanti M., Athanasiadou-Piperopoulou F., & Moschovi M. |
| Journal | Pediatr Blood Cancer |
| Volume | 54 |
| Issue | 2 |
| Pagination | 311-5 |
| Date Published | 2010 Feb |
| ISSN | 1545-5017 |
| Λέξεις κλειδιά | Adiponectin, Adolescent, Case-Control Studies, Child, Child, Preschool, Female, Greece, Hodgkin Disease, Humans, Infant, Infant, Newborn, Leptin, Logistic Models, Male, Multivariate Analysis, Risk Factors |
| Abstract | This case-control study aims to explore the association of serum adiponectin/leptin with childhood Hodgkin lymphoma (HL). Study participants were 75 children with histologically confirmed HL, registered in the Nationwide Registry for Childhood Haematological Malignancies and 75 age- and gender-matched controls. Multiple conditional logistic regression analyses were performed, adjusting for sociodemographic and lifestyle parameters. Adiponectin levels were consistently higher among cases in all models with ORs >1.25; 95% CIs ranging from 0.9 to 1.8 and P-values from 0.09 to 0.20. By contrast, there was no association of serum leptin with HL. In conclusion, elevated serum adiponectin might be a risk factor for childhood HL. |
| DOI | 10.1002/pbc.22294 |
| Alternate Journal | Pediatr Blood Cancer |
| PubMed ID | 19856392 |
