Underweight, overweight and obesity in paediatric dialysis and renal transplant patients.
Τίτλος | Underweight, overweight and obesity in paediatric dialysis and renal transplant patients. |
Publication Type | Journal Article |
Year of Publication | 2013 |
Authors | Bonthuis, M., van Stralen K. J., Verrina E., Groothoff J. W., Melgar Á. Alonso, Edefonti A., Fischbach M., Mendes P., Molchanova E. A., Paripović D., Peco-Antic A., Printza N., Rees L., Rubik J., Stefanidis C. J., Sinha M. D., Zagożdżon I., Jager K. J., & Schaefer F. |
Journal | Nephrol Dial Transplant |
Volume | 28 Suppl 4 |
Pagination | iv195-iv204 |
Date Published | 2013 Nov |
ISSN | 1460-2385 |
Λέξεις κλειδιά | Adolescent, Body Mass Index, Child, Child, Preschool, Female, France, Humans, Infant, Infant, Newborn, Kidney Failure, Chronic, Kidney Transplantation, Male, Nutritional Status, Obesity, Overweight, Prevalence, Renal Dialysis, Risk Factors, Thinness |
Abstract | BACKGROUND: The prevalence of childhood overweight is rising worldwide, but in children on renal replacement therapy (RRT) a poor nutritional status is still the primary concern. We aimed to study the prevalence of, and factors associated with, underweight and overweight/obesity in the European paediatric RRT population. Moreover, we assessed the evolution of body mass index (BMI) after the start of RRT.METHODS: We included 4474 patients younger than 16 years from 25 countries of whom BMI data, obtained between 1995 and 2010, were available within the European Society for Paediatric Nephrology/European Renal Association-European Dialysis and Transplant Association Registry. Prevalence estimates for under- and overweight/obesity were calculated using age and sex-specific criteria of the World Health Organization (WHO, 0-1 year olds) and the International Obesity Task Force cut-offs (2-15 year olds).RESULTS: The prevalence of underweight was 3.5%, whereas 20.8% of the patients were overweight and 12.5% obese. Factors associated with being underweight were receiving dialysis treatment and infant age. Among transplanted recipients, a very short stature (OR: 1.64, 95% CI: 1.40-1.92) and glucocorticoid treatment (OR: 1.23, 95% CI: 1.03-1.47) were associated with a higher risk of being overweight/obese. BMI increased post-transplant, and a lower BMI and a higher age at the start of RRT were associated with greater BMI changes during RRT treatment.CONCLUSIONS: Overweight and obesity, rather than underweight, are highly prevalent in European children on RRT. Short stature among graft recipients had a strong association with overweight, while underweight appears to be only a problem in infants. Our findings suggest that nutritional management in children receiving RRT should focus as much on the prevention and treatment of overweight as on preventing malnutrition. |
DOI | 10.1093/ndt/gft259 |
Alternate Journal | Nephrol. Dial. Transplant. |
PubMed ID | 23975752 |