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Acute laryngotracheobronchitis and associated transient hyperphosphatasemia: a new case of transient hyperphosphatasemia in early childhood.

ΤίτλοςAcute laryngotracheobronchitis and associated transient hyperphosphatasemia: a new case of transient hyperphosphatasemia in early childhood.
Publication TypeJournal Article
Year of Publication2006
AuthorsEboriadou, M., Skouli G., Panagopoulou P., Haidopoulou K., Makedou A., & Varlamis G.
JournalJ Paediatr Child Health
Volume42
Issue3
Pagination149-50
Date Published2006 Mar
ISSN1034-4810
Λέξεις κλειδιάAlkaline Phosphatase, Budesonide, Croup, Glucocorticoids, Humans, Infant, Isoenzymes, Male, Methylprednisolone, Nebulizers and Vaporizers, Phosphorus Metabolism Disorders, Treatment Outcome
Abstract

We report the case of a 20-month old boy with markedly elevated serum alkaline phosphatase (ALP) levels, documented during an episode of acute laryngotracheobronchitis. Biochemical investigations and imaging studies revealed no evidence of bone or liver disease. Transient hyperphosphatasemia (TH) was confirmed when serum ALP levels normalized within 2 months. Several theories were suggested for TH pathophysiology, viral infections among them; the exact causes, however, remain unclear. It is important to recognize TH and avoid misdiagnosis and unnecessary investigations.

DOI10.1111/j.1440-1754.2006.00817.x
Alternate JournalJ Paediatr Child Health
PubMed ID16509919

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