Anemia is associated with mortality following endovascular repair of abdominal aortic aneurysm.
| Τίτλος | Anemia is associated with mortality following endovascular repair of abdominal aortic aneurysm. |
| Publication Type | Journal Article |
| Year of Publication | 2012 |
| Authors | Saratzis, A., Melas N., Hunter J. P., Dixon H., Nightingale P., Kiskinis D., Saratzis N., & Kitas G. D. |
| Journal | Vasc Endovascular Surg |
| Volume | 46 |
| Issue | 3 |
| Pagination | 223-8 |
| Date Published | 2012 Apr |
| ISSN | 1938-9116 |
| Λέξεις κλειδιά | Aged, Anemia, Aortic Aneurysm, Abdominal, Biological Markers, Blood Vessel Prosthesis Implantation, C-Reactive Protein, Comorbidity, Endovascular Procedures, Female, Great Britain, Humans, Inflammation Mediators, Kaplan-Meier Estimate, Male, Middle Aged, Proportional Hazards Models, Prospective Studies, Registries, Risk Assessment, Risk Factors, Time Factors, Treatment Outcome, Up-Regulation |
| Abstract | AIM: The aim of this study was to compare midterm mortality between anemic and nonanemic patients undergoing endovascular repair of abdominal aortic aneurysm and to assess a correlation with markers of inflammation.METHODS: Anemia was defined as hemoglobin <13 (men) and <12 g/dL (women). The impact of anemia and inflammatory markers on mortality was assessed using Kaplan-Meier curves and Cox regression.RESULTS: A total of 224 patients (12 females [5.36%]; age: 69.73 ± 8.72 years) were included; 102 (45.53%) were anemic. Median follow-up was 17 months (interquartile range: 7-25 months). Nine patients died (1.79%; 8 anemic vs 1 nonanemic). Survival was lower for patients with anemia (log-rank, P = .01). White blood cell count and C-reactive protein (CRP) differed significantly (P < .001 and P = .01). Anemia and CRP were associated with decreased survival (Cox regression, P = .01, hazard ratio [HR]: 0.35, 95% confidence interval: 0.14-0.84 and P = .002, HR: 1.18, 95% CI: 1.06-1.31).CONCLUSION: Patients with anemia had decreased survival over the midterm; inflammatory markers were higher among this group. |
| DOI | 10.1177/1538574412442251 |
| Alternate Journal | Vasc Endovascular Surg |
| PubMed ID | 22492108 |
