The Post-SIR-Spheres Surgery Study (P4S): Retrospective Analysis of Safety Following Hepatic Resection or Transplantation in Patients Previously Treated with Selective Internal Radiation Therapy with Yttrium-90 Resin Microspheres.
Τίτλος | The Post-SIR-Spheres Surgery Study (P4S): Retrospective Analysis of Safety Following Hepatic Resection or Transplantation in Patients Previously Treated with Selective Internal Radiation Therapy with Yttrium-90 Resin Microspheres. |
Publication Type | Journal Article |
Year of Publication | 2017 |
Authors | Pardo, F., Sangro B., Lee R-C., Manas D., Jeyarajah R., Donckier V., Maleux G., Pinna A. D., Bester L., Morris D. L., Iannitti D., Chow P. K., Stubbs R., Gow P. J., Masi G., Fisher K. T., Lau W. Y., Kouladouros K., Katsanos G., Ercolani G., Rotellar F., Bilbao J. I., & Schoen M. |
Journal | Ann Surg Oncol |
Volume | 24 |
Issue | 9 |
Pagination | 2465-2473 |
Date Published | 2017 Sep |
ISSN | 1534-4681 |
Λέξεις κλειδιά | Aged, Brachytherapy, Female, Hepatectomy, Humans, Liver Failure, Liver Neoplasms, Liver Transplantation, Male, Microspheres, Middle Aged, Postoperative Complications, Radiotherapy, Adjuvant, Retrospective Studies, Yttrium Radioisotopes |
Abstract | BACKGROUND: Reports show that selective internal radiation therapy (SIRT) may downsize inoperable liver tumors to resection or transplantation, or enable a bridge-to-transplant. A small-cohort study found that long-term survival in patients undergoing resection following SIRT appears possible but no robust studies on postsurgical safety outcomes exist. The Post-SIR-Spheres Surgery Study was an international, multicenter, retrospective study to assess safety outcomes of liver resection or transplantation following SIRT with yttrium-90 (Y-90) resin microspheres (SIR-Spheres; Sirtex). |
DOI | 10.1245/s10434-017-5950-z |
Alternate Journal | Ann Surg Oncol |
PubMed ID | 28653161 |