OCT4B1 isoform: the novel OCT4 alternative spliced variant as a putative marker of stemness.
| Title | OCT4B1 isoform: the novel OCT4 alternative spliced variant as a putative marker of stemness. |
| Publication Type | Journal Article |
| Year of Publication | 2009 |
| Authors | Papamichos, S. I., Kotoula V., Tarlatzis B. C., Agorastos T., Papazisis K., & Lambropoulos A. F. |
| Journal | Mol Hum Reprod |
| Volume | 15 |
| Issue | 5 |
| Pagination | 269-70 |
| Date Published | 2009 May |
| ISSN | 1460-2407 |
| Keywords | Alternative Splicing, Biological Markers, Cell Line, Embryonic Stem Cells, Humans, Octamer Transcription Factor-3, Protein Isoforms |
| Abstract | A novel OCT4 alternative spliced variant (OCT 4B1) is deduced to be the isoform present in 59 hESC lines characterised by the International Stem Cell Initiative (ISCI) rather than OCT4A as previously assumed. The new variant may be a more reliable marker of stemness than OCT4A and studies are needed to test this. |
| DOI | 10.1093/molehr/gap018 |
| Alternate Journal | Mol. Hum. Reprod. |
| PubMed ID | 19258399 |
