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Circulating fetuin-A in patients with pancreatic cancer: a hospital-based case-control study.

TitleCirculating fetuin-A in patients with pancreatic cancer: a hospital-based case-control study.
Publication TypeJournal Article
Year of Publication2014
AuthorsDalamaga, M., Polyzos S. A., Karmaniolas K., Chamberland J., Lekka A., Migdalis I., Papadavid E., Dionyssiou-Asteriou A., & Mantzoros C. S.
JournalBiomarkers
Volume19
Issue8
Pagination660-6
Date Published2014 Dec
ISSN1366-5804
KeywordsAged, alpha-2-HS-Glycoprotein, Biomarkers, Tumor, Case-Control Studies, Female, Hospitals, Humans, Male, Middle Aged, Pancreatic Neoplasms
Abstract

CONTEXT: A proteomic analysis has proposed fetuin-A (alpha-2-HS-glycoprotein) as a new potential marker for pancreatic cancer (PC).
OBJECTIVE: Circulating fetuin-A levels in patients with PC.
METHODS: Serum fetuin-A was measured in 81 cases with PC and 81 matched controls before the initiation of any treatment.
RESULTS: Serum fetuin-A was not independently associated with the presence of PC. Although there was a trend with higher fetuin-A levels across PC stages, comparisons of fetuin-A in patients within different PC prognostic stages revealed no differences.
CONCLUSIONS: Circulating fetuin-A was similar between patients and controls and was not associated with the disease severity.
DOI10.3109/1354750X.2014.974071
Alternate JournalBiomarkers
PubMed ID25347061

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