Characterization of silodosin and naftopidil in the treatment of bladder dysfunction in the spontaneously hypertensive rat.
Title | Characterization of silodosin and naftopidil in the treatment of bladder dysfunction in the spontaneously hypertensive rat. |
Publication Type | Journal Article |
Year of Publication | 2013 |
Authors | Saito, M., Shimizu S., Ohmasa F., Oikawa R., Tsounapi P., Dimitriadis F., Kinoshita Y., & Satoh K. |
Journal | Neurourol Urodyn |
Volume | 32 |
Issue | 4 |
Pagination | 393-8 |
Date Published | 2013 Apr |
ISSN | 1520-6777 |
Keywords | Adrenergic alpha-1 Receptor Antagonists, Animals, Blood Pressure, Body Weight, Circadian Rhythm, Indoles, Male, Muscle Contraction, Naphthalenes, Organ Size, Piperazines, Rats, Rats, Inbred SHR, Rats, Wistar, Urinary Bladder, Urinary Bladder Diseases, Urination |
Abstract | PURPOSE: As increasing evidence suggest that α(1)-blockers prevent benign prostatic hyperplasia related overactive bladder and nocturia in the human, we investigated the effects of silodosin and naftopidil on hypertension-related bladder dysfunction in the spontaneously hypertensive rat (SHR) model. |
DOI | 10.1002/nau.22297 |
Alternate Journal | Neurourol Urodyn |
PubMed ID | 22907830 |