Does coenzyme Q supplementation improve fertility outcomes in women undergoing assisted reproductive technology procedures? A systematic review and meta-analysis of randomized-controlled trials.
Title | Does coenzyme Q supplementation improve fertility outcomes in women undergoing assisted reproductive technology procedures? A systematic review and meta-analysis of randomized-controlled trials. |
Publication Type | Journal Article |
Year of Publication | 2020 |
Authors | Florou, P., Anagnostis P., Theocharis P., Chourdakis M., & Goulis D. G. |
Journal | J Assist Reprod Genet |
Volume | 37 |
Issue | 10 |
Pagination | 2377-2387 |
Date Published | 2020 Oct |
ISSN | 1573-7330 |
Abstract | OBJECTIVE: Increased oxidative stress has been identified as a pathogenetic mechanism in female infertility. However, the effect of specific antioxidants, such as coenzyme Q (CoQ), on the outcomes after assisted reproductive technologies (ART) has not been clarified. The aim of this study was to systematically review and meta-analyze the best available evidence regarding the effect of CoQ supplementation on clinical pregnancy (CPR), live birth (LBR), and miscarriage rates (MR) compared with placebo or no-treatment in women with infertility undergoing ART. |
DOI | 10.1007/s10815-020-01906-3 |
Alternate Journal | J Assist Reprod Genet |
PubMed ID | 32767206 |
PubMed Central ID | PMC7550497 |