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Polyclonal predominance of concurrently producing OXA-23 and OXA-58 carbapenem-resistant Acinetobacter baumannii strains in a pediatric intensive care unit.

TitlePolyclonal predominance of concurrently producing OXA-23 and OXA-58 carbapenem-resistant Acinetobacter baumannii strains in a pediatric intensive care unit.
Publication TypeJournal Article
Year of Publication2019
AuthorsKarampatakis, T., Tsergouli K., Politi L., Diamantopoulou G., Iosifidis E., Antachopoulos C., Karyoti A., Sdougka M., Tsakris A., & Roilides E.
JournalMol Biol Rep
Volume46
Issue3
Pagination3497-3500
Date Published2019 Jun
ISSN1573-4978
KeywordsAcinetobacter baumannii, Anti-Bacterial Agents, Bacterial Proteins, beta-Lactamases, Carbapenems, Drug Resistance, Bacterial, Humans, Intensive Care Units, Pediatric, Microbial Sensitivity Tests
Abstract

We report a predominance (64.7%) of polyclonal carbapenem-resistant Acinetobacter baumannii (CRAB) strains concurrently producing OXA-23 and OXA-58 carbapenemases in a pediatric intensive care unit in an endemic area. This is the first report of emergence of such double-OXA CRAB strains in a single unit worldwide.

DOI10.1007/s11033-019-04744-4
Alternate JournalMol Biol Rep
PubMed ID30989561

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