Systemic endotoxaemia following obstructive jaundice: the role of lactulose.
Title | Systemic endotoxaemia following obstructive jaundice: the role of lactulose. |
Publication Type | Journal Article |
Year of Publication | 2003 |
Authors | Koutelidakis, I., Papaziogas B., Giamarellos-Bourboulis E. J., Makris J., Pavlidis T., Giamarellou H., & Papaziogas T. |
Journal | J Surg Res |
Volume | 113 |
Issue | 2 |
Pagination | 243-7 |
Date Published | 2003 Aug |
ISSN | 0022-4804 |
Keywords | Acute Disease, Animals, Bacterial Translocation, Cholangitis, Cholestasis, Common Bile Duct, Endotoxemia, Gastrointestinal Agents, Lactulose, Ligation, Lipopolysaccharides, Male, Malondialdehyde, Models, Animal, Rabbits, Systemic Inflammatory Response Syndrome, Tumor Necrosis Factor-alpha |
Abstract | BACKGROUND: Obstructive jaundice is often accompanied by bacterial translocation and subsequent sepsis. The effect of lactulose in preventing that process was evaluated in an experimental model. Obstructive jaundice was induced in 23 rabbits after common bile duct ligation. |
DOI | 10.1016/s0022-4804(03)00209-9 |
Alternate Journal | J Surg Res |
PubMed ID | 12957136 |