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Malignant orbital schwannoma with massive intracranial recurrence.

TitleMalignant orbital schwannoma with massive intracranial recurrence.
Publication TypeJournal Article
Year of Publication2008
AuthorsMiliaras, G., Tsitsopoulos P. P., Asproudis I., Tsekeris P., & Polyzoidis K.
JournalActa Neurochir (Wien)
Volume150
Issue12
Pagination1291-4; discussion 1294
Date Published2008 Dec
ISSN0942-0940
KeywordsBrain Neoplasms, Cerebral Hemorrhage, Cranial Nerve Neoplasms, Diplopia, Fatal Outcome, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Neoplasm Invasiveness, Neoplasm Recurrence, Local, Neurilemmoma, Neurosurgical Procedures, Orbit, Orbital Neoplasms, Pain, Reoperation, Tomography, X-Ray Computed, Vision, Low
Abstract

BACKGROUND: A 62 year old male presented with progressive diplopia, left orbital pain and impairment of visual acuity.
METHOD AND FINDINGS: Neuroradiological investigation disclosed an orbital tumour. The lesion was totally excised. Histopathology examination revealed a malignant peripheral nerve sheath tumour (MPNST). The tumour recurred with intracranial extension. The patient died 13 months after the initial diagnosis.
CONCLUSIONS: To our knowledge, this is the first reported example of a massive intracranial recurrence of an orbital MPNST. The epidemiological features, clinical course and treatment of these lesions are discussed.
DOI10.1007/s00701-008-0159-3
Alternate JournalActa Neurochir (Wien)
PubMed ID19020795

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