Many patients with primary sclerosing cholangitis and increased serum levels of carbohydrate antigen 19-9 do not have cholangiocarcinoma.
Title | Many patients with primary sclerosing cholangitis and increased serum levels of carbohydrate antigen 19-9 do not have cholangiocarcinoma. |
Publication Type | Journal Article |
Year of Publication | 2011 |
Authors | Sinakos, E., Saenger A. K., Keach J., W Kim R., & Lindor K. D. |
Journal | Clin Gastroenterol Hepatol |
Volume | 9 |
Issue | 5 |
Pagination | 434-9.e1 |
Date Published | 2011 May |
ISSN | 1542-7714 |
Keywords | Adult, Aged, CA-19-9 Antigen, Carbohydrates, Cholangiocarcinoma, Cholangitis, Sclerosing, Female, Humans, Male, Middle Aged, Serum |
Abstract | BACKGROUND & AIMS: Patients with primary sclerosing cholangitis (PSC) have an increased incidence of cholangiocarcinoma (CCA). Carbohydrate antigen 19-9 (CA 19-9) is the main serum marker used to diagnose CCA, although increased levels of CA 19-9 are also associated with other hepatic complications. We evaluated the long-term outcomes in patients with PSC and significant increases in levels of CA 19-9. |
DOI | 10.1016/j.cgh.2011.02.007 |
Alternate Journal | Clin Gastroenterol Hepatol |
PubMed ID | 21334457 |