Tc-99m HMPAO labeled white blood cell imaging in a child with eosinophilic lung disease.
| Title | Tc-99m HMPAO labeled white blood cell imaging in a child with eosinophilic lung disease. |
| Publication Type | Journal Article |
| Year of Publication | 2008 |
| Authors | Moralidis, E., Papakonstantinou E., Arsos G., Boussios N., Koliouskas D., & Karakatsanis C. |
| Journal | Clin Nucl Med |
| Volume | 33 |
| Issue | 1 |
| Pagination | 38-40 |
| Date Published | 2008 Jan |
| ISSN | 0363-9762 |
| Keywords | Acetamides, Anti-Infective Agents, Child, Preschool, Humans, Leukemia, Myeloid, Acute, Leukocytes, Linezolid, Magnetic Resonance Imaging, Male, Oxazolidinones, Pulmonary Eosinophilia, Radionuclide Imaging, Radiopharmaceuticals, Staphylococcal Infections, Technetium Tc 99m Exametazime |
| Abstract | In radiolabeled leukocyte imaging, Tc-99m HMPAO has a significantly higher selectivity for eosinophils than neutrophils, but this may be clinically meaningful in disorders with eosinophilic infiltration. We present the case of a 2-year-old boy with infection who also developed drug-induced eosinophilic lung disease, as established later by bronchoalveolar lavage and discontinuation of the responsible antistaphylococcal agent. In the investigation of sepsis, diffusely increased pulmonary accumulation of Tc-99m HMPAO labeled leukocytes was observed. These findings were consistent with eosinophilic lung infiltration and underline the importance of clinical and laboratory data in the comprehensive interpretation of Tc-99m HMPAO labeled leukocytes scans. |
| DOI | 10.1097/RLU.0b013e31815c504c |
| Alternate Journal | Clin Nucl Med |
| PubMed ID | 18097257 |
