Spinal epidural extraskeletal Ewing sarcoma in an adolescent boy: a case report.
| Title | Spinal epidural extraskeletal Ewing sarcoma in an adolescent boy: a case report. |
| Publication Type | Journal Article |
| Year of Publication | 2006 |
| Authors | Athanassiadou, F., Tragiannidis A., Kourti M., Papageorgiou T., Kotoula V., Kontopoulos V., & Christoforidis J. |
| Journal | Pediatr Hematol Oncol |
| Volume | 23 |
| Issue | 3 |
| Pagination | 263-7 |
| Date Published | 2006 Apr-May |
| ISSN | 1521-0669 |
| Keywords | Adolescent, Antineoplastic Combined Chemotherapy Protocols, Back Pain, Biomarkers, Tumor, Chromosomes, Human, Pair 11, Chromosomes, Human, Pair 22, Combined Modality Therapy, Cyclophosphamide, DNA, Neoplasm, Doxorubicin, Epidural Space, Etoposide, Fractures, Compression, Fractures, Spontaneous, Humans, Ifosfamide, Laminectomy, Magnetic Resonance Imaging, Male, Mesna, Neoplasm Proteins, Oncogene Proteins, Fusion, Proto-Oncogene Protein c-fli-1, Radiotherapy, Adjuvant, Reverse Transcriptase Polymerase Chain Reaction, RNA-Binding Protein EWS, Sarcoma, Ewing, Soft Tissue Neoplasms, Spinal Fractures, Thoracic Vertebrae, Tomography, X-Ray Computed, Transcription Factors, Translocation, Genetic, Vincristine |
| Abstract | Extraskeletal Ewing sarcoma (EES) represents a rare soft tissue malignant neoplasm histologically similar to skeletal Ewing sarcoma. It occurs mainly in adolescents and young adults and commonly affects the paravertebral regions. The differential diagnosis includes other small, blue round cells tumors. The authors report a case of an EES involving the spinal epidural and paravertebral spaces in an adolescent boy. EES diagnosis was confirmed by features of histologic analysis and immunohistochemistry and by the presence of the t(11;22)(q24;q12) chromosomal translocation by reverse transcriptase-polymerase chain reaction. |
| DOI | 10.1080/08880010500506297 |
| Alternate Journal | Pediatr Hematol Oncol |
| PubMed ID | 16517542 |
