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An extremely rare case of synchronous occurrence in the larynx of intravascular lymphoma and in situ squamous cell carcinoma.

TitleAn extremely rare case of synchronous occurrence in the larynx of intravascular lymphoma and in situ squamous cell carcinoma.
Publication TypeJournal Article
Year of Publication2003
AuthorsHadjileontis, C. G., Kostopoulos I. S., Kaloutsi V. D., Nikolaou A. C., Kotoula V. A., & Papadimitriou C. S.
JournalLeuk Lymphoma
Volume44
Issue6
Pagination1053-7
Date Published2003 Jun
ISSN1042-8194
KeywordsAntigens, CD, Antineoplastic Combined Chemotherapy Protocols, Biopsy, Carcinoma in Situ, Carcinoma, Squamous Cell, Cyclophosphamide, Epirubicin, Humans, Immunohistochemistry, Laryngeal Neoplasms, Lymphoma, Male, Middle Aged, Prednisone, Time Factors, Treatment Outcome, Vascular Neoplasms, Vincristine
Abstract

We present the first case of laryngeal intravascular lymphoma coexisting with in situ squamous cell carcinoma. The patient, a 53 years old man, presented with hoarseness starting a year ago and underwent laryngoscopy, which revealed two nodular lesions on his right vocal cord. The histological and immunohistochemical examination of the biopsy specimens established the diagnosis of in situ squamous cell carcinoma coexisting with intravascular lymphoma of T-cell origin. Taking in consideration all the available references, the larynx has not until now been reported as a primary site of involvement of intravascular (angiotropic) lymphomas, nor as a secondary location in the systematic course of this disease. Furthermore no cases have been reported in the literature, concerning the synchronous affection of the larynx by this lymphoma and in situ laryngeal carcinoma, or other type of neoplasm.

DOI10.1080/1042819031000063426
Alternate JournalLeuk Lymphoma
PubMed ID12854909

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