Mediastinal gastroenteric cyst in a neonate containing respiratory-type epithelium and pancreatic tissue.
Title | Mediastinal gastroenteric cyst in a neonate containing respiratory-type epithelium and pancreatic tissue. |
Publication Type | Journal Article |
Year of Publication | 2009 |
Authors | Anagnostou, E., Soubasi V., Agakidou E., Papakonstantinou C., Antonitsis P., Antonitsis N., & Leontsini M. |
Journal | Pediatr Pulmonol |
Volume | 44 |
Issue | 12 |
Pagination | 1240-3 |
Date Published | 2009 Dec |
ISSN | 1099-0496 |
Keywords | Choristoma, Female, Humans, Infant, Newborn, Mediastinal Cyst, Pancreas, Respiratory Mucosa |
Abstract | Mediastinal gastroenteric cyst is an uncommon congenital malformation and a distinct histopathological entity within the family of foregut duplication cysts. This lesion is mainly encountered in neonates and infants. Histologically, it is characterized by double-layered smooth muscle wall and gastric lining mucosa. We report on a case of a 2-day-old girl, with a posterior mediastinal cystic mass associated with T3-T4 hemivertebrae, presenting with severe respiratory distress. The cyst was multilocular, surgically removed, and histopathologic analysis revealed that it was of gastroenteric type. However, in numerous areas of the lesion, respiratory-type epithelium was observed, as well as pancreatic tissue. After removal of the lesion the patient made an uneventful recovery and shows no signs of long-term pulmonary sequelae. We failed to demonstrate in the available literature the presence of this variable epithelial lining within a single mediastinal foregut cyst. In addition, pancreatic tissue within an intrathoracic enteric cyst has been reported only twice. |
DOI | 10.1002/ppul.21142 |
Alternate Journal | Pediatr. Pulmonol. |
PubMed ID | 19911364 |