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Prevalence of age-related maculopathy in older Europeans: the European Eye Study (EUREYE).

TitlePrevalence of age-related maculopathy in older Europeans: the European Eye Study (EUREYE).
Publication TypeJournal Article
Year of Publication2006
AuthorsAugood, C. A., Vingerling J. R., de Jong P. T. V. M., Chakravarthy U., Seland J., Soubrane G., Tomazzoli L., Topouzis F., Bentham G., Rahu M., Vioque J., Young I. S., & Fletcher A. E.
JournalArch Ophthalmol
Volume124
Issue4
Pagination529-35
Date Published2006 Apr
ISSN0003-9950
KeywordsAged, Aged, 80 and over, Cross-Sectional Studies, Europe, Female, Humans, Macular Degeneration, Male, Photography, Prevalence, Retrospective Studies, Surveys and Questionnaires
Abstract

OBJECTIVE: To estimate the prevalence of age-related maculopathy in an older population from 7 European countries.METHODS: Randomly sampled people 65 years and older were invited to an eye examination in centers across 7 European countries (Norway, Estonia, United Kingdom, France, Italy, Greece, and Spain). Fundus images of each eye were graded at a single reading center. Prevalence rates were calculated for stage of age-related maculopathy with 95% confidence intervals (CIs) estimated for clustered data.RESULTS: Of 5040 participants (45% response rate), 4753 (2128 men and 2625 women) had gradable fundus images. The prevalences were grade 0, 47.59% (95% CI, 43.53%-51.65%); grade 1, 36.48% (95% CI, 32.66%-40.30%); grade 2, 10.14% (95% CI, 8.92% to 11.37%); grade 3, 2.46% (95% CI, 1.79%-3.13%); and grade 4 (age-related macular degeneration [AMD]), 3.32% (95% CI, 2.52%-4.13%) and large drusen only (> or = 125 microm), 15.41% (95% CI, 13.61%-17.21%). The prevalence of geographic atrophic AMD was 1.2% (95% CI, 0.8%-1.7%) and of neovascular AMD, 2.3% (95% CI, 1.7%-2.9%). The prevalence of bilateral AMD was 1.4% (95% CI, 1.0%-1.8%).CONCLUSION: Age-specific prevalences of age-related maculopathy in the European Eye Study (EUREYE) are similar to other population-based studies in Western populations.

DOI10.1001/archopht.124.4.529
Alternate JournalArch Ophthalmol
PubMed ID16606879

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