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Prevalence of age-related macular degeneration in Greece: the Thessaloniki Eye Study.

TitlePrevalence of age-related macular degeneration in Greece: the Thessaloniki Eye Study.
Publication TypeJournal Article
Year of Publication2006
AuthorsTopouzis, F., Coleman A. L., Harris A., Anastasopoulos E., Yu F., Koskosas A., Pappas T., Mavroudis L., & M Wilson R.
JournalAm J Ophthalmol
Volume142
Issue6
Pagination1076-9
Date Published2006 Dec
ISSN0002-9394
KeywordsAge Distribution, Aged, Aged, 80 and over, Cross-Sectional Studies, Female, Greece, Humans, Macular Degeneration, Male, Middle Aged, Prevalence, Sex Distribution
Abstract

PURPOSE: To estimate the age- and gender-specific prevalence of age-related macular degeneration (AMD) in a population-based sample of subjects 60 years of age or older in Thessaloniki, Greece.DESIGN: Cross-sectional population-based study.METHODS: A total of 2554 subjects randomly identified from municipality registers in Thessaloniki underwent a complete ophthalmologic examination.RESULTS: Of the 3617 eligible subjects, 2554 (71%) participants completed a clinical examination. The prevalence was 2.5% for AMD, 1.4% for neovascular (NV) AMD, and 1.3% for geographic atrophy (GA). Bilateral AMD was present in 40% of AMD cases. The prevalence of AMD, NV, GA, and bilateral AMD increased with increasing age (P< .0001). No gender-specific statistically significant differences were noted. Of all participants with AMD, 67% were unaware of the diagnosis.CONCLUSIONS: The prevalence of AMD in Greece is comparable to that in other Caucasian populations. A dramatic increase in prevalence in people older than 80 years of age was observed.

DOI10.1016/j.ajo.2006.07.042
Alternate JournalAm J Ophthalmol
PubMed ID17157601

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