Delayed Laboratory Response to COVID-19 Caused by Molecular Diagnostic Contamination.
| Title | Delayed Laboratory Response to COVID-19 Caused by Molecular Diagnostic Contamination. |
| Publication Type | Journal Article |
| Year of Publication | 2020 |
| Authors | Mögling, R., Meijer A., Berginc N., Bruisten S., Charrel R., Coutard B., Eckerle I., Enouf V., Hungnes O., Korukluoglu G., Kossyvakis T., Mentis A., Molenkamp R., Muradrasoli S., Papa A., Pigny F., Thirion L., van der Werf S., & Reusken C. |
| Journal | Emerg Infect Dis |
| Volume | 26 |
| Issue | 8 |
| Pagination | 1944-1946 |
| Date Published | 2020 08 |
| ISSN | 1080-6059 |
| Keywords | Artifacts, Betacoronavirus, Clinical Laboratory Techniques, Coronavirus Infections, Delayed Diagnosis, Diagnostic Tests, Routine, DNA Primers, DNA Probes, Europe, Humans, Laboratories, Pandemics, Pathology, Molecular, Pneumonia, Viral, Reagent Kits, Diagnostic, Reverse Transcriptase Polymerase Chain Reaction, RNA Replicase, Viral Envelope Proteins |
| Abstract | The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) created an exceptional situation in which numerous laboratories in Europe simultaneously implemented SARS-CoV-2 diagnostics. These laboratories reported in February 2020 that commercial primer and probe batches for SARS-CoV-2 detection were contaminated with synthetic control material, causing delays of regional testing roll-out in various countries. |
| DOI | 10.3201/eid2608.201843 |
| Alternate Journal | Emerg Infect Dis |
| PubMed ID | 32433015 |
| PubMed Central ID | PMC7392437 |
