Cardiovascular risk factors and estimated 10-year risk of fatal cardiovascular events using various equations in Greeks with metabolic syndrome.
Title | Cardiovascular risk factors and estimated 10-year risk of fatal cardiovascular events using various equations in Greeks with metabolic syndrome. |
Publication Type | Journal Article |
Year of Publication | 2010 |
Authors | Chimonas, T., Athyros V. G., Ganotakis E., Nicolaou V., Panagiotakos D. B., Mikhailidis D. P., & Elisaf M. |
Corporate Authors | Assessing the Treatment Effect in Metabolic Syndrome Without Perceptible diabeTes(ATTEMPT) Collaborative Group |
Journal | Angiology |
Volume | 61 |
Issue | 1 |
Pagination | 49-57 |
Date Published | 2010 Feb-Mar |
ISSN | 1940-1574 |
Keywords | Adult, Aged, Cardiovascular Diseases, Female, Greece, Humans, Male, Mathematics, Metabolic Syndrome X, Middle Aged, Prevalence, Risk Factors, Sex Distribution, Sex Factors, Time Factors |
Abstract | We investigated cardiovascular disease (CVD) risk factors in 1501 Greeks (613 men and 888 women, aged 40-65 years) referred to outpatients with metabolic syndrome (MetS) and without diabetes mellitus or CVD. The 10-year risk of fatal CVD events was calculated using European Society of Cardiology Systematic Coronary Risk Estimation (ESC SCORE), Hellenic-SCORE, and Framingham equations. Raised blood pressure (BP) and hypertriglyceridemia were more common in men (89.6% vs 84.2% and 86.8% vs 74.2%, respectively; P < .001). Low high-density lipoprotein cholesterol (HDL-C) and abdominal obesity were more common in women (58.2% vs 66.2% and 85.8% vs 97.1%, respectively; P < .001). The 10-year risk of fatal CVD events using HellenicSCORE was higher in men (6.3% +/- 4.3% vs 2.7% +/- 2.1%; P < .001). European Society of Cardiology Systematic Coronary Risk Estimation and Framingham yielded similar results. The risk equations gave similar assessments in a European Mediterranean population except for HellenicSCORE that calculated more MetS women requiring risk modification. This might justify local risk engine evaluation in event-based studies. (Clinical-Trials.gov ID: NCT00416741). |
DOI | 10.1177/0003319709351873 |
Alternate Journal | Angiology |
PubMed ID | 20034959 |