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Murine Typhus with Marked Thrombocytopenia in a Child in Northern Greece and Literature Review.

TitleMurine Typhus with Marked Thrombocytopenia in a Child in Northern Greece and Literature Review.
Publication TypeJournal Article
Year of Publication2018
AuthorsSarikloglou, E., Goula A., Sidiropoulos C., Tsolia M., & Papa A.
JournalJpn J Infect Dis
Volume71
Issue5
Pagination368-369
Date Published2018 Sep 21
ISSN1884-2836
KeywordsAnimals, Child, Preschool, Greece, Humans, Male, Mice, Polymerase Chain Reaction, Rickettsia typhi, Sequence Analysis, DNA, Thrombocytopenia, Typhus, Endemic Flea-Borne
Abstract

We report a case of murine typhus in a 4-year-old boy living in northern Greece. Although the illness started with mild symptoms, a maculopapular rash appeared by the end of the first week of illness followed by marked thrombocytopenia. The detection of IgM antibodies against Rickettsia typhi in the patient's blood and a positive polymerase chain reaction result combined with sequencing confirmed the diagnosis of infection by Rickettsia typhi. Clinicians in northern Greece should be aware of the disease, even in cases presenting with no specific initial symptoms.

DOI10.7883/yoken.JJID.2018.091
Alternate JournalJpn J Infect Dis
PubMed ID29848847

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