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Seven Non-melanoma Features to Rule Out Facial Melanoma.

TitleSeven Non-melanoma Features to Rule Out Facial Melanoma.
Publication TypeJournal Article
Year of Publication2017
AuthorsTschandl, P., Gambardella A., Boespflug A., Deinlein T., de Giorgi V., Kittler H., Lallas A., Malvehy J., Moscarella E., Puig S., Scalvenzi M., Thomas L., Zalaudek I., Alfano R., & Argenziano G.
JournalActa Derm Venereol
Volume97
Issue10
Pagination1219-1224
Date Published2017 Nov 15
ISSN1651-2057
KeywordsAlgorithms, Decision Support Techniques, Dermoscopy, Diagnosis, Differential, Facial Neoplasms, Humans, Italy, Pilot Projects, Predictive Value of Tests, Prevalence, Retrospective Studies, Skin, Skin Neoplasms
Abstract

Facial melanoma is difficult to diagnose and dermatoscopic features are often subtle. Dermatoscopic non-melanoma patterns may have a comparable diagnostic value. In this pilot study, facial lesions were collected retrospectively, resulting in a case set of 339 melanomas and 308 non-melanomas. Lesions were evaluated for the prevalence (> 50% of lesional surface) of 7 dermatoscopic non-melanoma features: scales, white follicles, erythema/reticular vessels, reticular and/or curved lines/fingerprints, structureless brown colour, sharp demarcation, and classic criteria of seborrhoeic keratosis. Melanomas had a lower number of non-melanoma patterns (p< 0.001). Scoring a lesion suspicious when no prevalent non-melanoma pattern is found resulted in a sensitivity of 88.5% and a specificity of 66.9% for the diagnosis of melanoma. Specificity was higher for solar lentigo (78.8%) and seborrhoeic keratosis (74.3%) and lower for actinic keratosis (61.4%) and lichenoid keratosis (25.6%). Evaluation of prevalent non-melanoma patterns can provide slightly lower sensitivity and higher specificity in detecting facial melanoma compared with already known malignant features.

DOI10.2340/00015555-2759
Alternate JournalActa Derm Venereol
PubMed ID28761960

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