Seven Non-melanoma Features to Rule Out Facial Melanoma.
Title | Seven Non-melanoma Features to Rule Out Facial Melanoma. |
Publication Type | Journal Article |
Year of Publication | 2017 |
Authors | Tschandl, P., Gambardella A., Boespflug A., Deinlein T., de Giorgi V., Kittler H., Lallas A., Malvehy J., Moscarella E., Puig S., Scalvenzi M., Thomas L., Zalaudek I., Alfano R., & Argenziano G. |
Journal | Acta Derm Venereol |
Volume | 97 |
Issue | 10 |
Pagination | 1219-1224 |
Date Published | 2017 Nov 15 |
ISSN | 1651-2057 |
Keywords | Algorithms, Decision Support Techniques, Dermoscopy, Diagnosis, Differential, Facial Neoplasms, Humans, Italy, Pilot Projects, Predictive Value of Tests, Prevalence, Retrospective Studies, Skin, Skin Neoplasms |
Abstract | Facial melanoma is difficult to diagnose and dermatoscopic features are often subtle. Dermatoscopic non-melanoma patterns may have a comparable diagnostic value. In this pilot study, facial lesions were collected retrospectively, resulting in a case set of 339 melanomas and 308 non-melanomas. Lesions were evaluated for the prevalence (> 50% of lesional surface) of 7 dermatoscopic non-melanoma features: scales, white follicles, erythema/reticular vessels, reticular and/or curved lines/fingerprints, structureless brown colour, sharp demarcation, and classic criteria of seborrhoeic keratosis. Melanomas had a lower number of non-melanoma patterns (p< 0.001). Scoring a lesion suspicious when no prevalent non-melanoma pattern is found resulted in a sensitivity of 88.5% and a specificity of 66.9% for the diagnosis of melanoma. Specificity was higher for solar lentigo (78.8%) and seborrhoeic keratosis (74.3%) and lower for actinic keratosis (61.4%) and lichenoid keratosis (25.6%). Evaluation of prevalent non-melanoma patterns can provide slightly lower sensitivity and higher specificity in detecting facial melanoma compared with already known malignant features. |
DOI | 10.2340/00015555-2759 |
Alternate Journal | Acta Derm Venereol |
PubMed ID | 28761960 |