Accuracy of dermatoscopy for the diagnosis of nonpigmented cancers of the skin.
| Title | Accuracy of dermatoscopy for the diagnosis of nonpigmented cancers of the skin. |
| Publication Type | Journal Article |
| Year of Publication | 2017 |
| Authors | Sinz, C., Tschandl P., Rosendahl C., Akay B. Nisa, Argenziano G., Blum A., Braun R. P., Cabo H., Gourhant J-Y., Kreusch J., Lallas A., Lapins J., Marghoob A. A., Menzies S. W., Paoli J., Rabinovitz H. S., Rinner C., Scope A., H Soyer P., Thomas L., Zalaudek I., & Kittler H. |
| Journal | J Am Acad Dermatol |
| Volume | 77 |
| Issue | 6 |
| Pagination | 1100-1109 |
| Date Published | 2017 Dec |
| ISSN | 1097-6787 |
| Keywords | Adolescent, Adult, Aged, Aged, 80 and over, Child, Dermoscopy, Female, Humans, Male, Middle Aged, Prospective Studies, Reproducibility of Results, Skin Neoplasms, Young Adult |
| Abstract | BACKGROUND: Nonpigmented skin cancer is common, and diagnosis with the unaided eye is error prone.OBJECTIVE: To investigate whether dermatoscopy improves the diagnostic accuracy for nonpigmented (amelanotic) cutaneous neoplasms.METHODS: We collected a sample of 2072 benign and malignant neoplastic lesions and inflammatory conditions and presented close-up images taken with and without dermatoscopy to 95 examiners with different levels of experience.RESULTS: The area under the curve was significantly higher with than without dermatoscopy (0.68 vs 0.64, P < .001). Among 51 possible diagnoses, the correct diagnosis was selected in 33.1% of cases with and 26.4% of cases without dermatoscopy (P < .001). For experts, the frequencies of correct specific diagnoses of a malignant lesion improved from 40.2% without to 51.3% with dermatoscopy. For all malignant neoplasms combined, the frequencies of appropriate management strategies increased from 78.1% without to 82.5% with dermatoscopy.LIMITATIONS: The study deviated from a real-life clinical setting and was potentially affected by verification and selection bias.CONCLUSIONS: Dermatoscopy improves the diagnosis and management of nonpigmented skin cancer and should be used as an adjunct to examination with the unaided eye. |
| DOI | 10.1016/j.jaad.2017.07.022 |
| Alternate Journal | J Am Acad Dermatol |
| PubMed ID | 28941871 |
