Independent validation of metric optimized gating for fetal cardiovascular phase-contrast flow imaging.
Title | Independent validation of metric optimized gating for fetal cardiovascular phase-contrast flow imaging. |
Publication Type | Journal Article |
Year of Publication | 2019 |
Authors | Bidhult, S., Töger J., Heiberg E., Carlsson M., Arheden H., Aletras A. H., & Hedström E. |
Journal | Magn Reson Med |
Volume | 81 |
Issue | 1 |
Pagination | 495-503 |
Date Published | 2019 01 |
ISSN | 1522-2594 |
Keywords | Algorithms, Aorta, Thoracic, Blood Flow Velocity, Cardiac-Gated Imaging Techniques, Cardiovascular System, Female, Fetal Heart, Heart Rate, Humans, Image Interpretation, Computer-Assisted, Magnetic Resonance Imaging, Observer Variation, Phantoms, Imaging, Pregnancy, Prenatal Diagnosis, Pulsatile Flow, Reproducibility of Results, Umbilical Veins |
Abstract | PURPOSE: To validate metric optimized gating phase-contrast MR (MOG PC-MR) flow measurements for a range of fetal flow velocities in phantom experiments. 2) To investigate intra- and interobserver variability for fetal flow measurements at an imaging center other than the original site.METHODS: MOG PC-MR was compared to timer/beaker measurements in a pulsatile flow phantom using a heart rate (∼145 bpm), nozzle diameter (∼6 mm), and flow range (∼130-700 mL/min) similar to fetal imaging. Fifteen healthy fetuses were included for intra- and interobserver variability in the fetal descending aorta and umbilical vein.RESULTS: Phantom MOG PC-MR flow bias and variability was 2% ± 23%. Accuracy of MOG PC-MR was degraded for flow profiles with low velocity-to-noise ratio. Intra- and interobserver coefficients of variation were 6% and 19%, respectively, for fetal descending aorta; and 10% and 17%, respectively, for the umbilical vein.CONCLUSION: Phantom validation showed good agreement between MOG and conventionally gated PC-MR, except for cases with low velocity-to-noise ratio, which resulted in MOG misgating and underestimated peak velocities and warranted optimization of sequence parameters to individual fetal vessels. Inter- and intraobserver variability for fetal MOG PC-MR imaging were comparable to previously reported values. |
DOI | 10.1002/mrm.27392 |
Alternate Journal | Magn Reson Med |
PubMed ID | 30159933 |
PubMed Central ID | PMC6282515 |
Grant List | 20160554 / / Swedish Heart and Lung Foundation / International / / Swedish Research Council / International / / Medical Faculty at Lund University / International / / Region of Skåne, and the Greek General Secretariat for Research and Development via an Excellence grant / International / / Medical Faculty at Lund University, and Region of Skåne / International / / Greek General Secretariat for Research and Development via an Excellence grant / International |