Rheolytic thrombectomy in patients with acute coronary syndrome and large thrombus burden: initial and mid-term results from a single centre experience.
Title | Rheolytic thrombectomy in patients with acute coronary syndrome and large thrombus burden: initial and mid-term results from a single centre experience. |
Publication Type | Journal Article |
Year of Publication | 2010 |
Authors | Dardas, P., Mezilis N., Ninios V., Efthimiadis G. K., Tsikaderis D., Pagourelias E., & Pliakos C. |
Journal | Hellenic J Cardiol |
Volume | 51 |
Issue | 1 |
Pagination | 27-36 |
Date Published | 2010 Jan-Feb |
ISSN | 2241-5955 |
Keywords | Acute Coronary Syndrome, Aged, Angioplasty, Balloon, Coronary, Case-Control Studies, Coronary Thrombosis, Feasibility Studies, Female, Humans, Male, Middle Aged, Retrospective Studies, Thrombectomy, Treatment Outcome |
Abstract | INTRODUCTION: The presence of a large intracoronary thrombus burden is a major complicating factor during percutaneous coronary intervention (PCI) in patients with an acute coronary syndrome (ACS). The use of rheolytic thrombectomy (RT) has been proposed to prevent thrombus-related complications, with conflicting results. The purpose of this study was to identify the feasibility and safety of this approach.METHODS: We conducted a single-centre, retrospective, observational case-control study, comparing the outcomes of PCI in 26 consecutive patients with ACS and a large thrombus burden who underwent RT to those of a control group of 26 patients, matched with regard to artery location and initial TIMI flow grade.RESULTS: Despite the higher prevalence of acute ST-elevation myocardial infarction and the larger thrombus burden in the RT group, there was less incidence of distal embolisation/no-reflow and less use of vasoactive intracoronary agents. The final TIMI flow was identical in both groups. There was no difference between the two groups in the in-hospital and mid-term incidence of major adverse coronary events.CONCLUSIONS: In this study, the use of RT in patients with a large thrombus burden during acute PCI was both feasible and safe and reduced the incidence of initial no-reflow phenomenon. |
Alternate Journal | Hellenic J Cardiol |
PubMed ID | 20118041 |