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Brucella as a biological weapon.

TitleBrucella as a biological weapon.
Publication TypeJournal Article
Year of Publication2006
AuthorsPappas, G., Panagopoulou P., Christou L., & Akritidis N.
JournalCell Mol Life Sci
Volume63
Issue19-20
Pagination2229-36
Date Published2006 Oct
ISSN1420-682X
KeywordsAnimals, Bioterrorism, Brucella, Brucellosis, Disease Outbreaks, Humans
Abstract

Brucella has traditionally been considered a biological weapon. It was the subject of extensive offensive research in the past, and still belongs to category B pathogens on most lists. Its propensity for airborne transmission and induction of chronic debilitating disease requiring combined antibiotic regimens for treatment, its abundance around the world and its vague clinical characteristics defying rapid clinical diagnosis are some of the characteristics that apply to the pathogen's weapons potential. Yet minimal mortality, availability of treatment options, protracted inoculation period and the emergence of new, more virulent potential weapons means that its inclusion among agents of bioterrorism is nowadays mainly of historical significance. Nevertheless, in the interest of literacy and of avoiding panic, physicians and the public both should be aware of the most common zoonosis worldwide.

DOI10.1007/s00018-006-6311-4
Alternate JournalCell Mol Life Sci
PubMed ID16964579

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