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Small cell carcinoma in ulcerative colitis--new treatment option: a case report.

TitleSmall cell carcinoma in ulcerative colitis--new treatment option: a case report.
Publication TypeJournal Article
Year of Publication2010
AuthorsKosmidis, C., Efthimiadis C., Anthimidis G., Vasiliadou K., Tzeveleki I., Fotiadis P., & Basdanis G.
JournalWorld J Surg Oncol
Volume8
Pagination100
Date Published2010
ISSN1477-7819
KeywordsAdenocarcinoma, Adult, Colitis, Ulcerative, Colonic Pouches, Colonoscopy, Humans, Magnetic Resonance Imaging, Male, Proctocolectomy, Restorative, Prognosis, Rectal Neoplasms, Small Cell Lung Carcinoma
Abstract

BACKGROUND: The most common type of carcinoma associated with ulcerative colitis (UC) is adenocarcinoma. We present a case of primary rectal small cell carcinoma in a patient with a history of UC.METHODS: A 34-year-old male diagnosed with UC for 10 years was not consistent with the usual annual follow-up and presented with mucoid-bloody diarrhea. Colonoscopy revealed a rectal mass 2 cm distant from the anal verge. The patient underwent a total proctocolectomy with preservation of the anal sphincters, construction of an ileal reservoir, anastomosis of the reservoir to the anus (J configuration) and protective loop ileostomy.RESULTS: Histological examination showed undifferentiated small cell carcinoma.CONCLUSIONS: This is the first case of small cell carcinoma in a background of UC reported to be treated surgically and the patient and has no recurrence 18 months postoperatively.

DOI10.1186/1477-7819-8-100
Alternate JournalWorld J Surg Oncol
PubMed ID21087512
PubMed Central IDPMC2999595

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