HeartCycle is an integrated project aiming to provide a disease management solution for cardiovascular disease patients, by developing technologies, algorithms to interpret data and services to facilitate the remote management of patients at home. In this paper an overview of part of the algorithmic work package, oriented at motivating the patients to be compliant to treatment regimes and to adopt a beneficial lifestyle, will be given. A concept allowing further education of the patient on the effect of medication on their vital signs, as well as the prediction of medication effect and a possible way to check compliance using vital signs measurements will be presented.