Should ambulatory blood pressure monitoring be mandatory for future studies in resistant hypertension: a perspective.
| Title | Should ambulatory blood pressure monitoring be mandatory for future studies in resistant hypertension: a perspective. |
| Publication Type | Journal Article |
| Year of Publication | 2012 |
| Authors | Doumas, M., Anyfanti P., & Bakris G. |
| Journal | J Hypertens |
| Volume | 30 |
| Issue | 5 |
| Pagination | 874-6 |
| Date Published | 2012 May |
| ISSN | 1473-5598 |
| Keywords | Antihypertensive Agents, Blood Pressure, Blood Pressure Determination, Blood Pressure Monitoring, Ambulatory, Clinical Trials as Topic, Equipment and Supplies, Europe, Humans, Hypertension, Multicenter Studies as Topic, Sympathetic Nervous System, White Coat Hypertension |
| Abstract | Recent technologic advances rekindled interventional management of resistant hypertension, either by carotid baroreceptor activation or renal sympathetic denervation. Interventional techniques result in impressive falls in office blood pressure (BP); however, ambulatory BP reductions are rather modest. This disparity between office and ambulatory BP reductions is observed with antihypertensive drugs, but at a much lower degree. Available explanations are not convincing, therefore, we propose that sympathetic overactivity may partially explain this divergence. Further studies are needed to prove or disprove our hypothesis. |
| DOI | 10.1097/HJH.0b013e328352c3c7 |
| Alternate Journal | J. Hypertens. |
| PubMed ID | 22495128 |
