Cyclosporine therapy during pregnancy in a patient with β-thalassemia major and autoimmune haemolytic anemia: a case report and review of the literature.
| Title | Cyclosporine therapy during pregnancy in a patient with β-thalassemia major and autoimmune haemolytic anemia: a case report and review of the literature. |
| Publication Type | Journal Article |
| Year of Publication | 2013 |
| Authors | Agapidou, A., Vlachaki E., Theodoridis T., Economou M., & Perifanis V. |
| Journal | Hippokratia |
| Volume | 17 |
| Issue | 1 |
| Pagination | 85-7 |
| Date Published | 2013 Jan |
| ISSN | 1108-4189 |
| Abstract | Recent advances in the management of hemoglobinopathies offer an improved potential for safe pregnancy with favourable outcome in patients with β-thalassemia major. Autoimmune diseases that are common in women at reproductive age might be fulminant and hardly manageable in pregnant women with thalassemia. Thus immunosuppressant drugs like cyclosporine A could be necessary in order to maintain good maternal and foetal health. We present a case report of a 35-year-old woman with β-thalassemia major, splenectomy, autoimmune hemolytic anemia and insulin treated diabetes mellitus who was treated with cyclosporine A during her pregnancy, and delivered a healthy male infant. First line therapy with steroids was ineffective, due to deregulation of diabetes mellitus. |
| Alternate Journal | Hippokratia |
| PubMed ID | 23935353 |
| PubMed Central ID | PMC3738288 |
