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Effects of moxonidine on sympathetic nervous system activity: An update on metabolism, cardio, and other target-organ protection.

TitleEffects of moxonidine on sympathetic nervous system activity: An update on metabolism, cardio, and other target-organ protection.
Publication TypeJournal Article
Year of Publication2013
AuthorsKarlafti, E. F., Hatzitolios A. I., Karlaftis A. F., Baltatzi M. S., Koliakos G. G., & Savopoulos C. G.
JournalJ Pharm Bioallied Sci
Volume5
Issue4
Pagination253-6
Date Published2013 Oct
ISSN0976-4879
Abstract

Moxonidine is the newest, second-generation, centrally acting antihypertensive agent. It has selective agonist activity at imidazoline I1 receptors and less adverse effects than the other centrally acting drugs. This fact authorizes the frequent use of moxonidine in clinical practice, as monotherapy or in combination with other antihypertensive agents. Also, moxonidine has beneficial effects in obese and metabolic syndrome and in target-organs, such as heart and kidneys.

DOI10.4103/0975-7406.120067
Alternate JournalJ Pharm Bioallied Sci
PubMed ID24302832
PubMed Central IDPMC3831737

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