Single-center experience of transplantation for polycystic liver disease.
| Title | Single-center experience of transplantation for polycystic liver disease. |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Vernadakis, S., Moris D., Mamarelis G., Fouzas I., Mathe Z., Kaiser G., Paul A., & Sotiropoulos G. |
| Journal | Transplant Proc |
| Volume | 46 |
| Issue | 9 |
| Pagination | 3209-11 |
| Date Published | 2014 Nov |
| ISSN | 1873-2623 |
| Keywords | Adult, Aged, Cysts, Female, Follow-Up Studies, Germany, Humans, Liver Diseases, Liver Transplantation, Male, Middle Aged, Retrospective Studies, Survival Rate, Time Factors |
| Abstract | BACKGROUND: Polycystic liver disease (PLD) may lead to massive hepatomegaly, abdominal distension, pain, and various degrees of dyspnea. The surgical treatment of this entity remains controversial.METHODS: We report our experience from a retrospective analysis of 23 patients suffering from PLD who were treated with liver transplantation (LT) in our institution.RESULTS: Liver transplantation for PLD patients with extensive hepatic involvement offers excellent symptoms relief. The actuarial 1-, 3-, and 5-year survival rate after transplantation was 86%.CONCLUSIONS: Our experience demonstrates that PLD patients with extensive hepatic involvement and who are treated with LT have good long-term prognosis and excellent symptoms relief. LT might be considered in severe PLD cases where conventional surgery is not a curative option, and it must be balanced against the risks of LT and lifelong commitment to immunosuppression. |
| DOI | 10.1016/j.transproceed.2014.09.158 |
| Alternate Journal | Transplant. Proc. |
| PubMed ID | 25420861 |
