Matrix metalloproteinases and peripheral arterial disease.
| Title | Matrix metalloproteinases and peripheral arterial disease. |
| Publication Type | Journal Article |
| Year of Publication | 2015 |
| Authors | Giagtzidis, I., Karkos C., Pitoulias G., & Papazoglou K. |
| Journal | Int Angiol |
| Volume | 34 |
| Issue | 3 |
| Pagination | 195-201 |
| Date Published | 2015 Jun |
| ISSN | 1827-1839 |
| Keywords | Angioplasty, Balloon, Animals, Biomarkers, Comorbidity, Diabetes Mellitus, Disease Progression, Extracellular Matrix, Humans, Hypertension, Matrix Metalloproteinases, Peripheral Arterial Disease, Renal Insufficiency, Chronic |
| Abstract | It has been postulated that atherosclerosis should be considered as a chronic inflammatory process and peripheral arterial disease (PAD) is a manifestation of such an atherosclerotic vascular disease. Matrix metalloproteinases (MMPs) are significant circulating biomarkers which play a pivotal role in the initiation, progression and clinical manifestations of PAD. This review summarizes the current body of evidence with regard to the association between MMPs and PAD. |
| Alternate Journal | Int Angiol |
| PubMed ID | 25069487 |
