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Consequences of hyperthyroidism in male and female fertility: pathophysiology and current management.

TitleConsequences of hyperthyroidism in male and female fertility: pathophysiology and current management.
Publication TypeJournal Article
Year of Publication2016
AuthorsMintziori, G., Kita M., Duntas L., & Goulis D. G.
JournalJ Endocrinol Invest
Volume39
Issue8
Pagination849-53
Date Published2016 Aug
ISSN1720-8386
KeywordsDisease Management, Female, Humans, Hyperthyroidism, Infertility, Male
Abstract

Thyroid hormone acts on the oocytes, sperm and embryo during fertilization, implantation and placentation. Both hypothyroidism and hyperthyroidism may influence fertility. However, evidence of the association of hyperthyroidism with infertility is scarce and sometimes conflicting. Thyroid hormone influences human reproduction via a variety of mechanisms at both the central and the peripheral level. Infertility may occur in hyperthyroid men and women, but it is usually reversible upon restoration of euthyroidism. This review aims to summarize the available data on the association of hyperthyroidism and infertility in both men and women and to provide practical suggestions for the management of these patients.

DOI10.1007/s40618-016-0452-6
Alternate JournalJ. Endocrinol. Invest.
PubMed ID26956000

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