The effect of teriparatide on serum Dickkopf-1 levels in postmenopausal women with established osteoporosis.
Τίτλος | The effect of teriparatide on serum Dickkopf-1 levels in postmenopausal women with established osteoporosis. |
Publication Type | Journal Article |
Year of Publication | 2010 |
Authors | Anastasilakis, A. D., Polyzos S. A., Avramidis A., Toulis K. A., Papatheodorou A., & Terpos E. |
Journal | Clin Endocrinol (Oxf) |
Volume | 72 |
Issue | 6 |
Pagination | 752-7 |
Date Published | 2010 Jun |
ISSN | 1365-2265 |
Λέξεις κλειδιά | Aged, Bone Density, Bone Density Conservation Agents, Calcium, Female, Follow-Up Studies, Humans, Intercellular Signaling Peptides and Proteins, Lumbar Vertebrae, Middle Aged, Osteoporosis, Postmenopausal, Parathyroid Hormone, Teriparatide |
Abstract | OBJECTIVE: Parathyroid hormone increases the differentiation of osteoblast precursors through canonical wingless (Wnt) signalling, resulting in an osteoanabolic effect. We aimed to evaluate serum levels of the Wnt-inhibitor Dickkopf-1 (Dkk-1) in postmenopausal women with established osteoporosis and their changes with teriparatide (TPTD - human recombinant PTH 1-34). |
DOI | 10.1111/j.1365-2265.2009.03728.x |
Alternate Journal | Clin. Endocrinol. (Oxf) |
PubMed ID | 19832854 |