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In vitro evaluation of the cytotoxicity of calcium hydroxide-based root canal sealers.

ΤίτλοςIn vitro evaluation of the cytotoxicity of calcium hydroxide-based root canal sealers.
Publication TypeJournal Article
Year of Publication1995
AuthorsBeltes, P., Koulaouzidou E., Kotoula V., & Kortsaris A. H.
JournalEndod Dent Traumatol
Volume11
Issue5
Pagination245-9
Date Published1995 Oct
ISSN0109-2502
Λέξεις κλειδιάAnimals, Calcium Hydroxide, Cells, Cultured, Cricetinae, Evaluation Studies as Topic, Fibroblasts, Kidney, L Cells, Mice, Root Canal Filling Materials, Salicylates, Zinc Oxide
Abstract

The cytotoxicity of three calcium hydroxide-containing root canal sealers (Sealapex, CRCS and Apexit) was tested by using L929 and BHK 21/C13 cells. After setting for 24 h, the sealers were covered with cell suspension. Cytotoxicity was determined by a quantitative technique at 24 h, 48 h and 72 h. All the sealers were found to be cytotoxic. Sealapex showed the highest cytotoxicity, causing a significant decrease in cell density. CRCS was less toxic than Sealapex and more toxic than Apexit. Apexit proved to be the least toxic material.

DOI10.1111/j.1600-9657.1995.tb00497.x
Alternate JournalEndod Dent Traumatol
PubMed ID8625940

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