In vitro evaluation of the cytotoxicity of calcium hydroxide-based root canal sealers.
| Title | In vitro evaluation of the cytotoxicity of calcium hydroxide-based root canal sealers. |
| Publication Type | Journal Article |
| Year of Publication | 1995 |
| Authors | Beltes, P., Koulaouzidou E., Kotoula V., & Kortsaris A. H. |
| Journal | Endod Dent Traumatol |
| Volume | 11 |
| Issue | 5 |
| Pagination | 245-9 |
| Date Published | 1995 Oct |
| ISSN | 0109-2502 |
| Keywords | Animals, Calcium Hydroxide, Cells, Cultured, Cricetinae, Evaluation Studies as Topic, Fibroblasts, Kidney, L Cells, Mice, Root Canal Filling Materials, Salicylates, Zinc Oxide |
| Abstract | The cytotoxicity of three calcium hydroxide-containing root canal sealers (Sealapex, CRCS and Apexit) was tested by using L929 and BHK 21/C13 cells. After setting for 24 h, the sealers were covered with cell suspension. Cytotoxicity was determined by a quantitative technique at 24 h, 48 h and 72 h. All the sealers were found to be cytotoxic. Sealapex showed the highest cytotoxicity, causing a significant decrease in cell density. CRCS was less toxic than Sealapex and more toxic than Apexit. Apexit proved to be the least toxic material. |
| DOI | 10.1111/j.1600-9657.1995.tb00497.x |
| Alternate Journal | Endod Dent Traumatol |
| PubMed ID | 8625940 |
